That's a serious issue.

Well, that's a tough one.

Attribution is, indeed, a serious problem.

This is a very serious problem

This is a very important issue

A growing challenge for the developing world

The increase in juvenile delinquency is a serious problem.

We are facing a very serious problem.

And this is a serious clinical problem.

And so this is a very serious problem.

If that's your attitude You have got a serious problem You really have a serious problem

Drought and desertification are another subject of major concern.

There was a tremendous banditry problem.

Therein lies the big problem with Earth Hour.

Unstable prices for commodities were a serious issue.

This is a serious problem that we're losing our listening.

And so, this makes this coming century a challenge.

The only problem here, and it's a big one, is that there is no insulin in the bloodstream.

Clearly there is a serious humanitarian issue involved.

This is a serious problem that may take time to be resolved.

For a real web crawler, this is a big challenge.

And so this is a very serious problem. Where is it coming from?

The worst problem in these terms relates to the Gaza Strip.

So I'm here to tell you that we have a problem with boys, and it's a serious problem with boys.

We put it in. There was a tremendous banditry problem.

The problem was a serious one, since the issue had wide political ramifications.

But the deeper problem lies elsewhere, in the poverty of the leadership, and in the fragmentation of Palestinian politics.

Tuberculosis is a hidden disease, but a much bigger problem than headline grabbing Ebola.

The 'plague' of cancer is at the center of a major public health crisis in China.

The United Nations Commission on Human Rights has a serious credibility problem.

Eastern Europe also poses a challenge for the future.

If the function turns out to have a weakness in it, well, that's a much more serious problem.

I said the carastana on the Tagabroo is a very serious problem, to say nothing of the larasang fay.

The first and most serious one, depending particularly on where one comes from, is the issue of violence and security.

But I believe that this is a big problem, a problem with potentially dangerous consequences for us as a society, as a culture and as individuals.

She contacted Caroline, who knew about it, and immediately identified the problem as serious.

Another major handicap is the absence of a children's court in the 12 districts of Sierra Leone.

Well here is a fundamental problem we have not solved our basic political geography.

The illicit trade in nuclear materials is a challenge to the international system of non proliferation of nuclear weapons.

However, security of supply, especially for the thermal systems, is essential and CCGT stations should be backed up by both an emergency fuel and stand by heat only boilers.

Last but not least is the health care issue.

It is a serious problem, one that many people in Pakistan, and beyond, are victims.

External debt servicing was a serious challenge to developing countries and economies in transition, especially in Africa.

A very serious problem is breast cancer, which is the No. 1 oncological disease among women.

The ability to fulfil their humanitarian mandates in conflict situations is an issue of most serious concern to humanitarian organizations.